Vladimir Semyonovich Saltykov was born into the family of S.A. Saltykov, the commander-in-chief of Moscow. In January 1741 he was commissioned as a brigadier and appointed ober-kommandant in Moscow with his bureau in the Moscow military office.
On 21 January 1742, Count Saltykov was placed in charge of the Moscow gubernia office. From 1 October to December 1742, and from July to December 1744, he was the acting head of the Moscow gubernia in the absence of the commander-in-chief and the governor-general.
To mark the coronation of Empress Elizabeth in 1742, wooden gates designed by the architect I. Michurin were erected. Later, during the governorship of S.A. Golitsyn, these gates, known as the Krasnye (Red) Gates, were replaced with stone copies made by D.V. Ukhtomsky. That same year (1742), work began on the Senate building in Lefortovo (architect I. Michurin). In 1749 the Moscow School of Architecture, founded by D.V. Ukhtomsky, opened its doors. Its students were to include V.I. Bazhenov, I.Ye. Starov and M.E Kazakov.
At the end of the 1740s, huge belfries were erected, one next to the Church of Nikita the Martyr on Staraya Basmannaya and another in the Donskoi Monastery. The decorative elements previously characteristic of government buildings and the residences of the aristocracy now begin to spread to all buildings erected in the city.
Count Saltykov was buried at the Nikita Convent in Moscow.
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